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THE TRAUNER RESEARCH GROUP

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Denksport

2019-09-09
Total Synthesis of (-)-Vindorosine

W. Chen, X.-D. Yang, W.-Y. Tan, X.-Y. Zhang, X.-L. Liao, H. Zhang Angew. Chem. Int. Ed. 2017, 56, 12327–12331.

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2019-09-02
Total Syntheses of Rhodomolleins XX and XXII

Yu, K.; Yang, Z-N.; Liu, C-H.; Wu, S-Q.; Hong, X.; Zhao, X-L.; Ding, H. Angew. Chem. Int. Ed. 2019, 58, 8556-8560.

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2019-08-26
Enantioselective Total Synthesis of (+)-Flavisiamine F via Late-Stage Visible-Light-Induced Photochemical Cyclization

X. Tong, B. Shi , K. Liang, Q. Liu , C. Xia Angew. Chem. Int. Ed. 2019, 58, 5443–5446.

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2019-08-19
Total Synthesis of 1-Hydroxytaxinine

Imamura, Y.; Yoshioka, S.; Nagatomo, M.; Inoue, M. Angew. Chem. Int. ed. 2019, 58, 12159-12163.

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2019-08-12
Total Synthesis and Isolation of Citrinalin and Cyclopiamine Congeners

E. V. Mercado-Marin, P. Garcia-Reynaga, S. Romminger, E. F. Pimenta, D. K. Romney, M. W. Lodewyk, D. E. Williams, R. J. Andersen, S. J. Miller, D. J. Tantillo, R. G. S. Berlinck, R. Sarpong Nature 2014, 509, 318-324.

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2019-08-05
Chemoenzymatic Total Synthesis of ent-Oxycodone: Fourth generation

Makarova, M.; Endoma-Arias, M. A. A.; Dela Paz, H. E.; Simionescu, R.; Hudlicky, T. J. Am. Chem. Soc. 2019, 141, 10883–10904.

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2019-07-29
Enantioselective Total Synthesis of (−)-Arcutinine

Wei Nie, Jing Gong, Zhihao Chen, Jiazhen Liu, Di Tian, Hao Song, Xiao-Yu Liu, Yong Qin J. Am. Chem. Soc. 2019, 141, 9712-9718.

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2019-07-22
Total Synthesis of (±) Maoecrystal V

J. Gong, G. Lin, W. Sun, C.-C. Li, Z. Yang, J. Am. Chem. Soc. 2010, 132, 16745-16745.

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2019-07-15
Total Syntheses of Bisdehydroneostemoninine and Bisdehydrostemoninine by Catalytic Carbonylative Spirolactonization

Ma, K.; Yin, X.; Prof. Dai, M. Angew. Chem. Int. Ed. 2018, 57, 15209-15212.

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2019-07-08
13-Step Total Synthesis of Atropurpuran

Xie, S.; Chen, G.; Yan, H.; Hou, J.; He, Y.; Zhao, T.; Xu, J. J. Am. Chem. Soc. 2019, 141, 3435-3439.

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2019-07-01
Divergent Total Synthesis of Indoxamycins A, C, and F

He, C.; Zhu, C.; Dai, Z.; Tseng, C. C.; Ding, H. Angew. Chem. Int. Ed. 2013, 52, 13256-13260.

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2019-06-24
Synthesis of Conidiogenol

Hu, P.; Chi, H.; DeBacker, K. C.; Gong, X.; Keim, J. H.; Hsu, I. T.; Snyder, S. A. Nature 2019, 569, 703-707.

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2019-06-17
Total Synthesis of (+)-Granatumine A and Related Bislactone Limonoid Alkaloids via a Pyran to Pyridine Interconversion

Schuppe, A.; Zhao, Y.; Liu, Y.; Newhouse, T. J. Am. Chem. Soc. 2019, 141, 9191-9196.

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2019-06-10
Total Synthesis of (+)-Arborisidine

Zhou, Z.; Gao, A. X.; Snyder, S. A. J. Am. Chem. Soc. 2019, 141, 7715-7720.

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2019-06-03
Total Synthesis of the Glycosylated Macrolide Antibiotic Fidaxomicin

Kaufmann, E.; Hattori, H.; Miyatake-Ondozabal, H.; Gademann, K.; Org. Lett. 2015, 17, 3514–3517;

Miyatake-Ondozabal, H.; Kaufmann, E.; Gademann, K.; Angew. Chem. Int. Ed. 2015, 54, 1933–1936.

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2019-05-20
Total Synthesis of (±) Bukittinggine

Stafford, J. A.; Heathcock, C. H.; Clark, D. L. J. Org. Chem. 1992, 57, 2575-2585.

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2019-05-13
Asymmetric Total Synthesis of Cerorubenic Acid-III

Liu, X.; Liu, J.; Wu, J.; Huang, G.; Liang, R.; Chung, L. W.; Li, C.-C. J. Am. Chem. Soc. 019, 141, 2872–2877.

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2019-05-06
The Enantioselective Total Synthesis of Exochomine

Gao, A. X.; Hamada, T.; Snyder, S. A. Angew. Chem. Int. Ed. 2016, 55, 10301-10306.

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2019-04-29
Scalable Total Synthesis of (-)-Vinigrol

Yu, X.; Xiao, L.; Wang, Z.; Luo, T. J. Am. Chem. Soc. 2019, 141, 3440–3443.

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2019-04-22
Synthesis of Ambiguine P

Johnson, R. E.; Ree, H.; Hartmann, M.; Lang, L.; Sawano, S.; Sarpong, R. J. Am. Chem. Soc. 2019, 141, 2233–2237.

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2019-04-15
Total Synthesis of Epicolactone

Kravina, A. G.; Carreira, E. M. Angew. Chem. Int. Ed. 2018, 57, 13159-13162.

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2019-04-08
Asymmetric Synthesis of Batrachotoxin: Enantiomeric Toxins show Functional Divergence against NaV

Logan, M. M.; Toma, T.; Thomas-Tran, R.; Du Bois, J.; Science 2016, 354, 865–869.

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2019-04-01
Total Synthesis of (-)-Isoschizogamine

Y. Miura, N. Hayashi, S. Yokoshima, and T. Fukuyama,  J. Am. Chem. Soc. 2012, 134, 11995-11997.

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2019-03-25
A Scalable Total Synthesis of the Antitumor Agents Et‐743 and Lurbinectedin

He, W.; Zhang, Z.; Ma, D. J. Am. Chem. Soc. 2019, 58, 3972-3975.

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2019-03-18
Total Synthesis of Aplysiasecosterol A

Lu, Z.; Zhang, X.; Guo, Z.; Chen, Y.; Mu, T.; Li, A. J. Am. Chem. Soc. 2018, 140, 9211-9218.

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2019-03-11
Total Synthesis of Astellatol

Zhao, N.; Yin, S.; Xie, S.; Yan, H.; Ren, P.; Chen, G.; Chen, F.; Xu, J. Angew. Chem. Int. Ed. 2018, 57, 3386–3390.

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2019-03-04
Total Syntheses of Various Amphilectane and Serrulatane Diterpenoids

Yu, X.; Su, F.; Liu, C.; Yuan, H.; Zhao, S.; Zhou, Z.; Quan, T.; Luo, T. J. Am. Chem. Soc. 2016, 138, 6261-6270.

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2019-02-25
Total Synthesis of (−)-Nahuoic Acid Ci (Bii)

Liu, Q.; Deng, Y.; Smith, A. B., III J. Am. Chem. Soc. 2017, 139, 13668–13671

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2019-02-11
Total Syntheses of Highly Oxidized ent-Kaurenoid Pharicin A, Pharicinin B, 7-O-Acetylpseurata C, and Pseurata C: A [5+2] Cascade Approach

He, C.; Hu, J.; Wu, Y.; Ding, H. J. Am. Chem. Soc. 2017, 139, 6098–6101.

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2019-02-04
Formal Total Synthesis of (+)-Pleuromutilin

Farney, E. P.; Feng, S. S.; Schäfers, F.; Reisman, S. E. J. Am. Chem. Soc. 2018, 140, 1267-1270.

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2019-01-25
Total Synthesis of Isodihydrokoumine, (19Z)‑Taberpsychine, and (4R)‑Isodihydroukoumine N4‑Oxide

Kerkovius, J. K.; Kerr, M. A. J. Am. Chem. Soc. 2018, 140, 8415-8419. 

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2019-01-13
Synthesis of (±)‐Merrilactone A by a Desymmetrization Strategy

Liu, W.; Wang, B. Chem. Eur. J. 2018, 24, 16511-16515.

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2019-01-07
A Benzyne-Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossonidine (Davisine).

Kou, K., G., M.; Pflueger, J., Kiho, T., Morrill, L., C.; Fisher, E., L.; Clagg, K.; Lebold, T., P.; Kisunzu, J., K.; Sarpong, R. J. Am. Chem. Soc. 2018, 140, 8105-8109.

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2018-12-17
Catalytic Asymmetric Total Synthesis of (−)-Actinophyllic Acid

Cai, L.; Zhang, K.; Kwon, O. J. Am. Chem. Soc. 2016, 138, 3298-3301.

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2018-12-03
Intramolecular Photocycloaddtion-Cyclobutane Fragmentation: Total Synthesis of (±)-Silphinene

Crimmins, M. T.; Mascarella, S. W. J. Am. Chem. Soc. 1986, 108, 3435-3438.

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2018-11-26
Total Synthesis of (-)-Histrionicotoxin and (-)-Histronicotoxine 235A

Stork, G.; Zhao, K. J. Am. Chem. Soc. 1990, 112, 5875-5876.

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2018-11-19
Total Synthesis of (±)-Nakafuran-8

Uyehara, T., Sugimoto, M., Suzuki, I., Yamamoto, Y., J. Chem. Soc. Chem. Commun. 1989, 1841-1842.

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2018-11-12
Total Synthesis of (−)-Chromodorolide B By a Computationally-Guided Radical Addition/Cyclization/Fragmentation Cascade

Tao, D. J.; Slutskyy, Y.; Muuronen, M.; Le, A.; Kohler, P.; Overman, L. E. J. Am. Chem. Soc. 2018, 140, 3091-3102.

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2018-11-05
Bioinspired Total Synthesis of Sespenine

Sun, Y.; Chen, P.; Zhang, D.; Baunach, M.; Hertweck, C.; Li, A. Angew. Chem. Int. Ed.2014, 53, 9012-9016.

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2018-10-29
Enantioselective Total Synthesis of (+) and (–)-Nigellamine A2

Bian, J.; van Wingerden, M.; Ready, J., M. J. Am. Chem. Soc. 2006, 128, 7428–7429.

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2018-10-22
A Diosphenol-Based Strategy for the Total Synthesis of (–)-Terpestacin

Trost, B., M.; Dong, G.; Vance.; J. JACS 2005, 129, 4541.

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2018-10-15
Enantioselective Total Synthesis of (−)-Pavidolide B

Zhang, P.-P.; Yan, Z.-M.; Li, Y.-H.; Gong, J.-X.; Yang, Z. J. Am. Chem. Soc. 2017, 139, 13989–13992.

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2018-10-03
A Biomimetic Synthesis of (±)-Basiliolide B

Liang, X., Zhou, L., Min, L., Ye, W., Bao, W., Ma, W., Yang, Q., Qiao, F., Zhang, X., Lee, C.-S. Angew. Chem. Int. Ed. 2014, 53, 11294-11297.

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2018-09-10
Total Synthesis of Natural (-)-Echinosporin. Determination of the Absolute Configuration

Smith, A. B.; Sulikowski, A.; Fujimoto, K. J. Am. Chem. Soc. 1989, 111, 8039-8041.

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2018-09-07
Biomimetic Total Synthesis of the Pentacyclic Amaryllidaceae Alkaloid Derivative Gracilamine

Gao, N.; Banwell, M. G. and Willis, A. C. Org. Lett. 2017, 19, 162-165.

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2018-08-21
Total Synthesis of Securinega Alkaloids (-)-Norsecurinine, (-)-Niruroidine and (-)-Flueggine A

Ma, N.; Yao, Y.; Zhao, B. X.; Wang, Y.; Ye, W. C.; Jiang, S. Chem. Commun. 2014, 50, 9284-9287.

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2018-07-30
Total Synthesis of Actinophyllic Acid

Yoshii, Y.; Tokuyama, H.; Chen, D. Y.-K. Angew. Chem. Int. Ed. 2017, 56, 12277-12281.

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2018-07-17
A Concise Total Synthesis of Salinketal B

Liu, K; De Brabander, J. K; J. Am. Chem. Soc. 2009, 131, 12562

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2018-06-08
Studies on Total Synthesis of the Cytotoxic Marine Alkaloid Agelastatin A

Anderson, G. T.; Chase, C. E.; Koh, Y.-H.; Stien, D.; Weinreb, S. M. J. Org. Chem. 1998, 63, 7594.

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2018-05-07
A Modular and Enantioselective Synthesis of the Pleuromutilin Antibiotics

Murphy, s., K.; Zeng, M.; Herzon, S., B. Science 2017, 356, 956-959.

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2018-04-30
α-Ketenyl Radical Intermediates in the Synthesis of Propellanes. A Formal Synthesis of Modhephene

Boeck, B.; Pattenden, G. Tet. Lett. 1988, 39, 6975 – 6978.

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2018-03-26
Development, Mechanistic Elucidation, and Rational Optimization of a Tandem Ireland Claisen/Cope Rearrangement Reaction for Rapid Access to the (Iso)Cyclocitrinol Core

Plummer, C. W.; Wei, C. S.; Yozwiak, C. E.; Soheili, A.; Smithback, S. O.; Leighton, J. A. J. Am. Chem. Soc. 2014, 136, 9878-9881.

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2018-03-26
Development, Mechanistic Elucidation, and Rational Optimization of a Tandem Ireland Claisen/Cope Rearrangement Reaction for Rapid Access to the (Iso)Cyclocitrinol Core

C. W. Plummer, C. S. Wei, C. E. Yozwiak, A. Soheili, S. O. S., James L. Leighton J. Am. Chem. Soc., 2014, 136, 9878–9881.

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2018-02-06
Total Synthesis of (+)-Complanadine A Using an Iridium-Catalyzed Pyridine C-H Functionalization

Fischer, D., F.; Sarpong, R. J. Am. Chem. Soc. 2010, 132, 5926–592.

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2017-07-23
Total Synthesis of Unsymmetrically Oxidized Nuphar Thioalkaloids via Copper-Catalyzed Thiolane Assembly

Lacharity, J. J.; Fournier, J.; Ping, L.; Mailyan, A. K.; Herrmann, A. T.; Zakarian A. J. Am. Chem. Soc., 2017, 139, 13272–13275.

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2017-01-24
An Enantioselective Total Synthesis of (+)-Citrinadin B

Kong, K; Enquist, J.; McCallum, M; Smith, G.; Matsumaru, T.; Wood, J. L. J. Am. Chem. Soc. 2013, 135, 10890-10893.

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