Home
Research
Gallery
The Group
Dirk Trauner
Members
Alumni
Publications
Teaching
denksport
resources
contact
news

THE TRAUNER RESEARCH GROUP

Home
Research
Gallery
Publications
Teaching
Denksport
Resources
News
Contact

Denksport

2019-05-06
The Enantioselective Total Synthesis of Exochomine

Gao, A. X.; Hamada, T.; Snyder, S. A. Angew. Chem. Int. Ed. 2016, 55, 10301-10306.

[Problem]
|
[Key]
2019-04-29
Scalable Total Synthesis of (-)-Vinigrol

Yu, X.; Xiao, L.; Wang, Z.; Luo, T. J. Am. Chem. Soc. 2019, 141, 3440–3443.

[Problem]
|
[Key]
2019-04-22
Ambiguine P

Johnson, R. E.; Ree, H.; Hartmann, M.; Lang, L.; Sawano, S.; Sarpong, R. J. Am. Chem. Soc. 2019, 141, 2233–2237.

[Problem]
|
[Key]
2019-04-15
Total Synthesis of Epicolactone

Kravina, A. G.; Carreira, E. M. Angew. Chem. Int. Ed. 2018, 57, 13159-13162.

[Problem]
|
[Key]
2019-04-08
Asymmetric Synthesis of Batrachotoxin: Enantiomeric Toxins show Functional Divergence against NaV

Logan, M. M.; Toma, T.; Thomas-Tran, R.; Du Bois, J.; Science 2016, 354, 865–869.

[Problem]
|
[Key]
2019-04-01
Total Synthesis of (-)-Isoschizogamine

Y. Miura, N. Hayashi, S. Yokoshima, and T. Fukuyama,  J. Am. Chem. Soc. 2012, 134, 11995-11997.

[Problem]
|
[Key]
2019-03-25
A Scalable Total Synthesis of the Antitumor Agents Et‐743 and Lurbinectedin

He, W.; Zhang, Z.; Ma, D. J. Am. Chem. Soc. 2019, 58, 3972-3975.

[Problem]
|
[Key]
2019-03-18
Total Synthesis of Aplysiasecosterol A

Lu, Z.; Zhang, X.; Guo, Z.; Chen, Y.; Mu, T.; Li, A. J. Am. Chem. Soc. 2018, 140, 9211-9218.

[Problem]
|
[Key]
2019-03-11
Total Synthesis of Astellatol

Zhao, N.; Yin, S.; Xie, S.; Yan, H.; Ren, P.; Chen, G.; Chen, F.; Xu, J. Angew. Chem. Int. Ed. 2018, 57, 3386–3390.

[Problem]
|
[Key]
2019-03-04
Total Syntheses of Various Amphilectane and Serrulatane Diterpenoids

Yu, X.; Su, F.; Liu, C.; Yuan, H.; Zhao, S.; Zhou, Z.; Quan, T.; Luo, T. J. Am. Chem. Soc. 2016, 138, 6261-6270.

[Problem]
|
[Key]
2019-02-25
Total Synthesis of (−)-Nahuoic Acid Ci (Bii)

Liu, Q.; Deng, Y.; Smith, A. B., III J. Am. Chem. Soc. 2017, 139, 13668–13671

[Problem]
|
[Key]
2019-02-11
Total Syntheses of Highly Oxidized ent-Kaurenoid Pharicin A, Pharicinin B, 7-O-Acetylpseurata C, and Pseurata C: A [5+2] Cascade Approach

He, C.; Hu, J.; Wu, Y.; Ding, H. J. Am. Chem. Soc. 2017, 139, 6098–6101.

[Problem]
|
[Key]
2019-02-04
Formal Total Synthesis of (+)-Pleuromutilin

Farney, E. P.; Feng, S. S.; Schäfers, F.; Reisman, S. E. J. Am. Chem. Soc. 2018, 140, 1267-1270.

[Problem]
|
[Key]
2019-01-25
Total Synthesis of Isodihydrokoumine, (19Z)‑Taberpsychine, and (4R)‑Isodihydroukoumine N4‑Oxide

Kerkovius, J. K.; Kerr, M. A. J. Am. Chem. Soc. 2018, 140, 8415-8419. 

[Problem]
|
[Key]
2019-01-13
Synthesis of (±)‐Merrilactone A by a Desymmetrization Strategy

Liu, W.; Wang, B. Chem. Eur. J. 2018, 24, 16511-16515.

[Problem]
|
[Key]
2019-01-07
A Benzyne-Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossonidine (Davisine).

Kou, K., G., M.; Pflueger, J., Kiho, T., Morrill, L., C.; Fisher, E., L.; Clagg, K.; Lebold, T., P.; Kisunzu, J., K.; Sarpong, R. J. Am. Chem. Soc. 2018, 140, 8105-8109.

[Problem]
|
[Key]
2018-12-17
Catalytic Asymmetric Total Synthesis of (−)-Actinophyllic Acid

Cai, L.; Zhang, K.; Kwon, O. J. Am. Chem. Soc. 2016, 138, 3298-3301.

[Problem]
|
[Key]
2018-12-03
Intramolecular Photocycloaddtion-Cyclobutane Fragmentation: Total Synthesis of (±)-Silphinene

Crimmins, M. T.; Mascarella, S. W. J. Am. Chem. Soc. 1986, 108, 3435-3438.

[Problem]
|
[Key]
2018-11-26
Total Synthesis of (-)-Histrionicotoxin and (-)-Histronicotoxine 235A

Stork, G.; Zhao, K. J. Am. Chem. Soc. 1990, 112, 5875-5876.

[Problem]
|
[Key]
2018-11-19
Total Synthesis of (±)-Nakafuran-8

Uyehara, T., Sugimoto, M., Suzuki, I., Yamamoto, Y., J. Chem. Soc. Chem. Commun. 1989, 1841-1842.

[Problem]
|
[Key]
2018-11-12
Total Synthesis of (−)-Chromodorolide B By a Computationally-Guided Radical Addition/Cyclization/Fragmentation Cascade

Tao, D. J.; Slutskyy, Y.; Muuronen, M.; Le, A.; Kohler, P.; Overman, L. E. J. Am. Chem. Soc. 2018, 140, 3091-3102.

[Problem]
|
[Key]
2018-11-05
Bioinspired Total Synthesis of Sespenine

Sun, Y.; Chen, P.; Zhang, D.; Baunach, M.; Hertweck, C.; Li, A. Angew. Chem. Int. Ed.2014, 53, 9012-9016.

[Problem]
|
[Key]
2018-10-29
Enantioselective Total Synthesis of (+) and (–)-Nigellamine A2

Bian, J.; van Wingerden, M.; Ready, J., M. J. Am. Chem. Soc. 2006, 128, 7428–7429.

[Problem]
|
[Key]
2018-10-22
A Diosphenol-Based Strategy for the Total Synthesis of (–)-Terpestacin

Trost, B., M.; Dong, G.; Vance.; J. JACS 2005, 129, 4541.

[Problem]
|
[Key]
2018-10-15
Enantioselective Total Synthesis of (−)-Pavidolide B

Zhang, P.-P.; Yan, Z.-M.; Li, Y.-H.; Gong, J.-X.; Yang, Z. J. Am. Chem. Soc. 2017, 139, 13989–13992.

[Problem]
|
[Key]
2018-10-03
A Biomimetic Synthesis of (±)-Basiliolide B

Liang, X., Zhou, L., Min, L., Ye, W., Bao, W., Ma, W., Yang, Q., Qiao, F., Zhang, X., Lee, C.-S. Angew. Chem. Int. Ed. 2014, 53, 11294-11297.

[Problem]
|
[Key]
2018-09-10
Total Synthesis of Natural (-)-Echinosporin. Determination of the Absolute Configuration

Smith, A. B.; Sulikowski, A.; Fujimoto, K. J. Am. Chem. Soc. 1989, 111, 8039-8041.

[Problem]
|
[Key]
2018-09-07
Biomimetic Total Synthesis of the Pentacyclic Amaryllidaceae Alkaloid Derivative Gracilamine

Gao, N.; Banwell, M. G. and Willis, A. C. Org. Lett. 2017, 19, 162-165.

[Problem]
|
[Key]
2018-08-21
Total Synthesis of Securinega Alkaloids (-)-Norsecurinine, (-)-Niruroidine and (-)-Flueggine A

Ma, N.; Yao, Y.; Zhao, B. X.; Wang, Y.; Ye, W. C.; Jiang, S. Chem. Commun. 2014, 50, 9284-9287.

[Problem]
|
[Key]
2018-07-30
Total Synthesis of Actinophyllic Acid

Yoshii, Y.; Tokuyama, H.; Chen, D. Y.-K. Angew. Chem. Int. Ed. 2017, 56, 12277-12281.

‍

[Problem]
|
[Key]
2018-07-17
A Concise Total Synthesis of Salinketal B

Liu, K; De Brabander, J. K; J. Am. Chem. Soc. 2009, 131, 12562

[Problem]
|
[Key]
2018-06-08
Studies on Total Synthesis of the Cytotoxic Marine Alkaloid Agelastatin A

Anderson, G. T.; Chase, C. E.; Koh, Y.-H.; Stien, D.; Weinreb, S. M. J. Org. Chem. 1998, 63, 7594.

[Problem]
|
[Key]
2018-05-07
A Modular and Enantioselective Synthesis of the Pleuromutilin Antibiotics

Murphy, s., K.; Zeng, M.; Herzon, S., B. Science 2017, 356, 956-959.

[Problem]
|
[Key]
2018-04-30
α-Ketenyl Radical Intermediates in the Synthesis of Propellanes. A Formal Synthesis of Modhephene

Boeck, B.; Pattenden, G. Tet. Lett. 1988, 39, 6975 – 6978.

[Problem]
|
[Key]
2018-03-26
Development, Mechanistic Elucidation, and Rational Optimization of a Tandem Ireland Claisen/Cope Rearrangement Reaction for Rapid Access to the (Iso)Cyclocitrinol Core

Plummer, C. W.; Wei, C. S.; Yozwiak, C. E.; Soheili, A.; Smithback, S. O.; Leighton, J. A. J. Am. Chem. Soc. 2014, 136, 9878-9881.

[Problem]
|
[Key]
2018-03-26
Development, Mechanistic Elucidation, and Rational Optimization of a Tandem Ireland Claisen/Cope Rearrangement Reaction for Rapid Access to the (Iso)Cyclocitrinol Core

C. W. Plummer, C. S. Wei, C. E. Yozwiak, A. Soheili, S. O. S., James L. Leighton J. Am. Chem. Soc., 2014, 136, 9878–9881.

[Problem]
|
[Key]
2018-02-06
Total Synthesis of (+)-Complanadine A Using an Iridium-Catalyzed Pyridine C-H Functionalization

Fischer, D., F.; Sarpong, R. J. Am. Chem. Soc. 2010, 132, 5926–592.

[Problem]
|
[Key]
2017-07-23
Total Synthesis of Unsymmetrically Oxidized Nuphar Thioalkaloids via Copper-Catalyzed Thiolane Assembly

Lacharity, J. J.; Fournier, J.; Ping, L.; Mailyan, A. K.; Herrmann, A. T.; Zakarian A. J. Am. Chem. Soc., 2017, 139, 13272–13275.

[Problem]
|
[Key]
2017-01-24
An Enantioselective Total Synthesis of (+)-Citrinadin B

Kong, K; Enquist, J.; McCallum, M; Smith, G.; Matsumaru, T.; Wood, J. L. J. Am. Chem. Soc. 2013, 135, 10890-10893.

[Problem]
|
[Key]