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Publications

259

"Optical tools for understanding the complexity of β-cell signalling and insulin release" Frank, J. A.; Broichhagen, J.; Yushchenko, D., A.; Trauner, D.; Schultz, C.; Hodson, D., J. Nat Rev Endocrinol 2018, Article ASAP.

[DOI]
258

"Biomimetic Synthesis of (+)‐Aspergillin PZ" Reyes, J., Winter, N., Spessert, L., Trauner, D., Angew. Chem. Int. Ed. 2018, Article ASAP.

[DOI]
257

"Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors" Durand-de Cuttoli, R.; Mondo,loni, S.; Marti, F.; Lemoine, D.; Nguyen, C.; Naude, J.; D'Izarnt-Gargas, T.; Pons, S.; Maskos, U.; Trauner, D.; Kramer, R., H.; Faure, P.; Mourot, A. elife, 2018, Article ASAP

[DOI]
256

"Optical Control of a Delayed Rectifier and a Two-Pore Potassium Channel with a Photoswitchable Bupivacaine" Leippe, P.; Winter, N.; Sumser, M., P. ACS Chem. Neurosci. 2018, Article ASAP.

[DOI]
255

“A Versatile Bis-Allylboron Reagent for the Stereoselective Synthesis of Chiral Diols” Hetzler, B. E.; Volpin, G.; Vignoni, E.; Petrovic, A. P.; Proni, G; Chunhua, T, H.; Trauner, D.* Angew. Chem. Int. Ed. 2018, asap, http://DOI: 10.1002/anie.201808234.

[DOI]
254

"Optical Control of L-Type Ca2+Channels Using a Diltiazem Photoswitch" Fehrentz,T.; Huber, F. M. E.; Vrielink, N.; Bruegmann, T.; Frank, J. A.; Fine, N. H. F.; Malan, D.; Danzl, J. G.; Tikhonov, D. B.; Sasse, P.; Hodson, D. J.; Zhorov. B. S.; Klöcker, N.*; Trauner, D.* Nature Chem. Biol. 2018, 14, 764-767.

[DOI]
253

"In Vivo Photopharmacology" Hüll, K.; Morstein, J.; Trauner, D. Chem. Rev2018, asap, DOI: 10.1021/acs.chemrev.8b0003.

[DOI]
252

 "Total Synthesis of (±)-­Exotine B". Cheng, B.; Volpin, G.; Morstein, J.; Trauner., D. Org. Lett2018, 20 (14), 4358-4361.

[DOI]
251

Toward (−)-Enterocin: An Improved Cuprate Barbier Protocol To Overcome Strain and Sterical Hindrance" Rizzo. A.; Trauner, D. Org. Lett2018, 20, 1841–1844.

[DOI]
250

"Total Synthesis of the Norhasubanan Alkaloid Stephadiamine"Hartrampf, N.; Winter, N.; Pupo, G.; Stoltz, B.; Trauner, D.* J. Am. Chem. Soc. 2018, 140, 8675-8680.

[DOI]
249

"Azomethine Ylide Cycloaddition Approach toward Dendrobine: Synthesis of 5-Deoxymubironine C" Williams, B. M.; Trauner D. J. Org. Chem. 201883, 3061-3068.

[DOI]
248

 "Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology" Podewin, T.; Ast, J.; Broichhagen, J.; Fine, N. H. F.; Nateska, J.; Leippe, P.; Gailer, M.; Buenaventura, T.; Kanda. N.; Jones, B. J.; M’Kadmi, Z.; Baneres, J.-L.; Marie, J.; Tomas, A.; Trauner, D.;* Hoffmann-Röder, A.,* Hodson, D. J.* ACS Cent. Sci. 2018, 4, 166-179.

[DOI]
247

"A Predictive Approach for the Optical Control of Carbonic Anhydrase II Activity" DuBay, K. H.; Iwan, K.; Osorio-Planes, L.; Geissler, P. L.; Groll, M.; Trauner, D.; Broichhagen, J. ACS Chem. Biol.  201813, 793-800.

[DOI]
246

"SNAP-Tagged Nanobodies Enable Reversible Optical Control of a G Protein-Coupled Receptor via a Remotely Tethered Photoswitchable Ligand" Farrants, H.; Acosta Ruiz, A.; Gutzeit, V. A.; Trauner, D.; Johnsson, K.; Levitz, J.; Broichhagen, J. BioRxiv 2018, DOI: http://dx.doi.org/10.1101/266247.

[DOI]
245

"Optical Control of a Biological Reaction–Diffusion System" Glock, P.; Broichhagen, J.; Kretschmer, S.; Blumhardt, P.; Mücksch, J.; Trauner, D.*; Schwille, P.* Ange. Chem. Int. Ed.  201857, 2362-2366.

[DOI]
244

"Selective Synthesis of Divergolide I" Terwilliger, D.; Trauner, D. J. Am. Chem. Soc. 2018140, 2748-2751.

[DOI]
243

"Reversible Optical Control of F1F0-ATP Synthase Using Photoswitchable Inhibitors" Eisel, B.; Hartrampf, F. W. W.: Meier, T.;* Trauner, D.* FEBS Letters 2018, 592, 343–355.

[DOI]
242

Donthamsetti, P., C.; Winter, N.; Schönberger, M,; Levitz., J.; Stanley, C.; Javitch, J., A.; ISacoff, E., Y.; Trauner, D. J. Am. Chem. Soc., 2017, 139, 18522–18535.

[DOI]
241

"Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor" Berry, M., H.; Holt, A.; Levitz, J.; Broichhagen, J.; Gaub, B., M.; Visel, M.; Stanley, C.; Aghi, K.; Kim, J., J.; Cao. K.; Kramer, R., H.; Trauner, D.; Flannery, J.; Isacoff, E., Y.; Nat. Communications 2017, 1862.

[DOI]
240

"The Chemist and the Architect" Trauner, D. Angew. Chem. Int. Ed. 2018, 57, 4177-4191.

[DOI]
239

"PhoDAGs Enable Optical Control of Diacylglycerol-Sensitive Transient Receptor Potential Channels" Trese Leinders-Zufall, T.; Storch, U.; Bleymehl, K.; Mederos y Schnitzler, M.; Frank, J.: Konrad, D.; Trauner, D.; Gudermann, T.; Zufall, F. Cell Chemical Biology 201725, 215-223. 

[DOI]
238

"Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling" Westphal, M.; Schafroth, M.A.; Sarott, R.; Imhof, M.; Bold, C.; Leippe, P.; Dhopeshwarkar, A.; Grandner, J.; Katritch, V.; Mackie, K.; Trauner, D.;* Carreira,  E. M.;* Frank, J. A.* J. Am. Chem. Soc. 2017, 139, 18206-18212.

[DOI]
237

"Specificity and Speed: Tethered Photopharmacology" Leippe, P.; Koehler-Lemann, J.; Trauner, D. Biochemistry 201756, 5214-5220.

[DOI]
236

"Optical Control of GPR40 Signaling in Pancreatic β-Cells" Frank, J. A.; Yushchenko, D.; Hine, N. N. F.; Duca, M.; Citir, M.; Broichhagen, J.; Hodson,* D. A.; Schultz, C.;* Trauner. D.* Chem.Sci. 20178, 7604-7610.

[DOI]
235

"Total Synthesis of Crocagin A" Bihelovic, F.; Stichnoth, D.; Surup, F.; Müller, R.; Trauner, D. Angew. Chem. Int. Ed. 201756, 13028-13031.

[DOI]
234

"Biomimetic Synthesis of Complex Flavonoids Isolated From Daemonorops ‘Dragon's Blood’" Schmid, M.; Trauner, D. Angew. Chem. Int. Ed. 201756, 12332-12335.

[DOI]
232

"Thiocarbonyl Ylide Chemistry Enables a Concise Synthesis of (±)-Hippolachnin A " Winter, N.; Trauner, D. J. Am. Chem. Soc.2017139, 11706–11709.

[DOI]
231

"Total Synthesis of Lycopladine A and Carinatine A via a Base-Mediated Carbocyclization" Hartrampf, F.; Trauner, D. J. Org. Chem. 201782, 8206-8212.

[DOI]
231

"Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2" Cheng, B.; Müller, R.; Trauner, D. Angew. Chem. Int. Ed. 2017, 56, 12755-12759.

 

[DOI]
230

"Development of a Photoswitchable Antagonist of NMDA Receptors" Hartrampf, F. W. W.; Barber, D. M.; Gottschling, K.; Leippe, P.; Hollmann, M.; Trauner, D. Tetrahedron 2017, 73, 4905-4912.

[DOI]
229

"Asymmetric Synthesis of the Antiviral Diterpene Wickerol A" Liu, S.-A.; Trauner, D. J. Am. Chem. Soc. 2017239, 9491-9494.

[DOI]
228

"Wild-type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Aynaptic Fidelity via Tubulin Polymerization at the Calyx of Held " Eguchi, K.; Taoufiq, Z.; Thorn-Seshold, O.; Trauner, D.; Hasegawa, M.; Takahashi, T.; J. Neurosci. 201737, 6043-6052.

[DOI]
227

"Structure and Biosynthesis of Crocagins: Polycyclic Posttranslationally Modified Ribosomal Peptides from Chondromyces crocatus". Viehrig, K.: Surup, F.: Volz, C.: Herrmann, J.: Abou Fayad, A.: Adam, S.; Köhnke, J.; Trauner, D.: Mūller, R. Angew. Chem. Int. Ed. 201756, 7407-7410.

[DOI]
226

"Photopharmacological Control of Bipolar Cells Enables the Restoration of Visual Function" Laprell, L.; Tochitsky, I.; Kaur, K.; Manookin, M. B.; Stein, M.; Barber, D. M.; Schoen, C.; Michalakis, S.; Biel, Kramer R. H.: Sumser, M.; Trauner, D.; * Van Gelder, R. N. * J. Clin. Invest. 2017, DOI:10.1172/JCI92156.

[DOI]
225

"A Photoswitchable Inhibitor of a Glutamate Transporter" Cheng. B.; Shchepakin, B.; Kavanaugh, M.;* Trauner, D.* ACS Chem Neurosci. 20178, 1668-1672.

[DOI]
224

"Light-Controlled Membrane Mechanics and Shape Transitions of Photoswitchable Lipid Vesicles" Pernpeintner, C.; Frank, J. A.; Urban, P.; Roeske, C. R.; Pritzl, S. D.; Trauner, D.;* Lohmüller, T.* Langmuir201733, 4083-4089.

[DOI]
223

"Optical Control of a Receptor-linked Guanylyl Cyclase Using a Photoswitchable Peptidic Hormone" Podewin, T.; Broichhagen, J.; Frost, C.; Groneberg, D.; Ast, J.; Meyer-Berg, H.; Fine, N. H. F.; Friebe, A.; Zacharias, M.; Hodson, D. J.; Trauner, D.;* Hoffmann-Röder, A.*Chem. Sci20178, 4644-4653.

[DOI]
222

"Dual Optical Control and Mechanistic Insights Into Photoswitchable Group II and III Metabotropic Glutamate Receptors" Levitz, J.; Broichhagen, J.; Leippe, P.; Konrad, D.; Trauner D: Isacoff, E. Y. Proc. Natl. Acad. Sci. USA 2017114, E3546–E3554.

[DOI]
221

"Selective Lithiation, Magnesiation and Zincation of Unsymmetrical Azobenzenes Using Continuous Flow" Ketels, M.; Konrad, D.; Karaghiosoff, K.; Trauner, D;* Knochel, P.* Org. Lett. 201719, 1666–1669.

[DOI]
220

"Remote Control of Glucose Homeostasis in vivo Using Photopharmacology" Mehta, Z. B.; Johnston, N. R.; Nguyen-Tu, M.-S.; Broichhagen, J.; Schultz, P.; Larner, D. P.; Leclerc, I.; Trauner, D;* Rutter, G. A.;* Hodson, D. J.* Sci. Rep. 20177, 291DOI: 10.1038/s41598- 017-00397-0.

[DOI]
219

"Furans as Versatile Synthons: Total Syntheses of Caribenol A and Caribenol B" Hao, H.; Trauner. D. J. Am. Chem. Soc. 2017239, 12981-12986.

[DOI]
218

"Unravelling Photochemical Relationships Amongst Natural Products from Aplysia dactylomela" Matsuura, B. S.; Kölle, P.; de Vivie-Riedle, R.*; Trauner, D.*; Meier, R.* ACS Central Sci. 20173, 39-46.

[DOI]

Open Access

217

"A Conia-Ene-Type Cyclization Under Basic Conditions Enables an Efficient Synthesis of (−)-Lycoposerramine R" Hartrampf, F.; Furukawa, T.; Trauner, D. Angew. Chem. Int. Ed.201756, 893-896.

[DOI]
216

"Enantioselective Synthesis and Racemization of (–)-Sinoracutine" Volpin, G; Veprek, N. A.; Bellan, A. B.; Trauner. D. Angew. Chem. Int. Ed. 201756, 897-901.

[DOI]
215

Optical Control of GIRK Channels Using Visible Light" Trads, J. B.; Burgstaller, J.; Laprell, L.; Konrad, D. B.; de la Osa de la Rosa, L.; Weaver, C. D.; Trauner. D.*; Barber, D.* Org. Biomol. Chem. 2017, 15, 76-81.

[DOI]
214

"Optical Control of Lipid Rafts with Photoswitchable Ceramides" Frank, J. A.; Franquelim, H. A.; Schwille, P.*; Trauner. D.* J. Am. Chem. Soc. 2016138, 12981-12986.

[DOI]
213

"Optical Control of AMPA Receptors Using a Photoswitchable Quinoxaline-2,3-dione Antagonist" Barber, D. M.; Liu, S.-A.; Gottschling, K.; Sumser, M.; Hollmann, M.; Trauner, D. Chem. Sci20178, 611-615.

[DOI]

Open Access

212

"Allosteric Optical Control of a Class B G-Protein-Coupled Receptor" Broichhagen, J., Johnston, N., R., Von Ohlen, Y., Meyer-Berg, H., Jones, B., J., Bloom, S., R., Rutter, G., A., Trauner. D., Hodson, D., J., Angew. Chem. Int. Ed. 2016, 5865-5868.

[DOI]
211

"Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose" Johnston, N. R.; Mitchell, R. K.; Haythorne, E.; Paiva Pessoa, M.; Semplici, F.; Ferrer, J.; Piemonti, L.; Marchetti, P.; Bugliani, M.; Bosco, D.; Berishvili, E.; Duncanson, P.; Watkinson, M.; Broichhagen, J.; Trauner, D.; Rutter, G. A.; Hodson, D. J. Cell Metab. 201624, 389-401.

[DOI]

Open Access

210

"Photoswitchable Diacylglycerols Enable Optical Control of Protein Kinase C" Frank, J. A.; Yushchenko, D.; Hodson, D. A.; Lipstein, N.; Nagpal, J.; Rutter, G. A.; Rhee, J.-S.; Gottschalk, A.; Brose, N.; Schultz, C.; Trauner. D. Nature Chem. Biol. 201612, 755-762.

[DOI]
209

"A Synthesis of (±)-Aplydactone" Meier, R., Trauner, D. Angew. Chem. Int. Ed. 201655, 11251-11255.

[DOI]

Highlighted in Synfacts

208

Damijonaitis, A.; Barber, D. M.; Trauner, D. The Photopharmacology of Nicotinic Acetylcholine Receptors. Neurotransmitter 3, 1292 (2016).

[DOI]
207

"A Family of Photoswitchable NMDA Receptors" Berlin, S.; Szobota, S.; Reiner, A.; Kienzler, M. A.; Guyon, A.; Trauner. D.; Isacoff. E. Y. eLife 2016, e12040, DOI: 10.7554/eLife.12040.

[DOI]

Open Access

206

"Synthesis of Red-shifted Azobenzene Photoswitches via Late-Stage Functionalization" Konrad, D.; Frank, J. A.; Trauner, D. Chem. Eur. J. 201622, 4364-4368.

[DOI]
205

“6-[6-(Pyridin-2-yl)-1,2,4,5-tetrazin-3-yl]pyridin-3-amine monohydrate” Broichhagen, J.; Klingl, Y. E.; Trauner, D.; Mayer, P. Acta Cryst. 2016, E72, 238-240.

[DOI]

Open Access

204

"Optical Control of Neuronal Activity Using a Light Operated GIRK-Channel Opener (LOGO)" Barber, D.; Schönberger, M.; Burgstaller, J.; Levitz, J.; Weaver, C. D.; Isacoff, E. Y.; Baier, H.; Trauner. D. Chem. Sci20167, 2347-2352.

[DOI]

Open Access

203

"Expedient Synthesis of Lycopalhine A" Williams. B., Trauner, D.* Angew. Chemie Int. Ed. 201655, 2191-2194.

[DOI]

Highlighted in Synfacts

202

"Synthetic Approaches Towards Alkaloids Bearing a-Tertiary Amines" Hager, A.; Vrielink, N.; Hager, D.; Lefranc, J.; Trauner, D. Nat. Prod. Rep. 2016, 33, 491-522.

[DOI]
201

"Inter-Kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway" Simon, S.; Schell, U.; Heuer, N.; Hager, D.; Albers, M. F.; Matthias, J.; Fahrnbauer, F.; Trauner, D.; Eichinger, L.; Hedberg, C.; Hilbi, H. PLOS Pathogens 2015, 11, e1005307.

[DOI]
200

"Restoring Light Sensitivity in Blind Retinae Using a Photochromic AMPA Receptor Agonist" Laprell, L.; Hüll, K.; Stawski, P.; Schön, C.; Michalakis, S.; Biel, M.; Sumser, M. P.; Trauner, D. ACS Chem. Neurosci20167, 15-20.

[DOI]

Highlighted as Front Cover

199

"Optical Control of Insulin Secretion Using an Incretin Switch" Broichhagen, J.; Podewin T.; Meyer-Berg, H.; von Ohlen, Y.; Johnston, N. R.; Jones, B. J.; Bloom, S. R.; Rutter, G. A.; Hoffmann-Röder, A.*; Hodson, D. J. *Trauner. D.* Angew. Chem. Int. Ed. 201554, 15565-15569.

[DOI]
198

"A Highly Convergent and Biomimetic Total Synthesis of Portentol" Cheng, B.; Trauner, D.J. Am. Chem. Soc. 2015137, 13800-13803.

[DOI]
197

"Orthogonal Optical Control of a G Protein-Coupled Receptor With a SNAP-Tethered Photochromic Ligand" Broichhagen, J.; Damijonaitis, A.; Levitz, J.; Sokol, K. R.; Leippe, P.; Konrad, D.; Isacoff, E. Y.; Trauner, D. ACS Central Sci. 20151, 383-393.

[DOI]
196

"Light-Dark Adaptation of Channelrhodopsin Involves Photoconversion Between the all-trans and 13-cis Retinal Isomers" Bruun, S.; Stoeppler, D.; Keidel. A.; Kuhlmann, U.; Luck, M.; Diehl, A.; Geiger M.A.; Woodmansee, D.; Trauner, D., Hegemann, P.; Oschkinat H.; Hildebrandt, P.; Stehfest, K. Biochemistry 201554, 5389-5400.

[DOI]
195

An Eight-Step Synthesis of Epicolactone Reveals its Biosynthetic Origin" Ellerbrock, P.; Armanino. N.; Ilg. M. K.; Webster, R.; Trauner, D. Nature Chemistry 2015, 7, 879-882.

[DOI]

Highlighted in Nature Chemistry and Synfacts

194

"Molecular Dynamics Investigation of Gluazo, a Photo-Switchable Ligand for the Glutamate" Guo, Y.; Wolter, T.; Kubař, T.; Sumser, M.; Trauner, D.; Elstner, M. PLoS One 201510, e0135399.

[DOI]
193

"Optical Control of NMDA-Receptors With a Diffusible Photoswitch" Laprell, L.; Repak, E.; Franckevicius, V.; Hartrampf, F.; Terhag, J.; Hollmann. M.; Sumser, M.; Rebola, N., DiGregorio, D.*; Trauner, D.* Nature Commun. 20156, 8076.

[DOI]

Open Access Article

192

"Richard Willstätter and the 1915 Nobel Prize in Chemistry" Trauner, D. Angew. Chem. Int. Ed. 201554, 11910-11916.

[DOI]
191

"Azobenzene-Based Inhibitors of Human Carbonic Anhydrase II" Runtsch, L. S.; Barber, D. M.; Mayer, P.; Groll, M.; Trauner, D.; Broichhagen, J. Beilstein J. Org. Chem. 201411, 1129-1135.

[DOI]
190

"Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death" Borowiak, M.; Nahaboo, W.; Reynders, M.; Nekolla, K.; Jalinot, P.; Hasserodt, J.; Rehberg, M.; Delattre, M.; Zahler, S.; Vollmar, A.; Trauner, D.*; Thorn-Seshold, O.* Cell 2015162, 403-411.

[DOI]

Highlights in EMBO Journal

Nat Chem Bio,

Cell Previews

The Economist

189

"Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer" Schneider, L. S.; von Schwarzenberg, K.; Lehr, T.; Ulrich, M.; Kubisch- Dohmen, R.; Liebl, J.; Trauner, D.; Menche, D.; Vollmar, A. M. Cancer Res. 201575, 2863-2874.

[DOI]
188

Evolution of a Unified Strategy for Complex Sesterterpenoids: Progress toward Astellatol and Total Synthesis of (−)-Nitidasin" Hog, D. T.; Huber, F. M. E.; Jiménez-Osés, G.*; Mayer, P.; Houk, K. N., Trauner, D.* Chem. Eur. J.201521, 13646-13665.

[DOI]
187

"A Roadmap to Success in Photopharmacology" Broichhagen, J.; Frank, J.A.; Trauner, D.Acc. Chem. Res.2015, 48, 1947-1960.

[DOI]
186

Crystal Structure of (E)-1,2-Bis­(4-bromo-2,6-di­fluoro­phen­yl)diazene" Broichhagen, J.; Woodmansee, D. H.; Trauner, D.; Mayer, P. Acta Crystallographica Section E: Structure Reports Online 201571, o459-o460.

[DOI]
185

"Photoswitchable Fatty Acids Enable Optical Control of TRPV1" Frank, J. A.; Moroni, M.; Moshourab, R.; Sumser, M.; Lewin, G. R.; Trauner, D. Nature Commun. 20156, 7188.

[DOI]

Open Access Article; Chemistry and Biology Select

184

"Molecular Aesthetics" Herausgegeben von Peter Weibel und Ljiljana Fruk" (Book Review) Trauner, D. Angew. Chemie Int. Ed. 201554, 7074.

[DOI]
183

"Biomimetic Total Synthesis of Santalin Y" Strych, S.; Journot, G.; Pemberton, R.P.; Wang, S. C.; Tantillo, D.*, Trauner, D.* Angew. Chem. Int. Ed. 201554, 5079-5083.

[DOI]

Highlighted as Front CoverHighlighted in Synfacts

182

"AzoCholine Enables Optical Control of Alpha 7 Nicotinic Acetylcholine Receptors in Neural Networks" Damijonaitis, A.; Broichhagen, J.; Urushima, T.; Hüll, K.; Nagpal, J.; Laprell, L.; Schönberger, M.; Woodmansee, David; Rafiq, A.; Sumser, M.; Kummer, W.; Gottschalk, A.; Trauner, D. ACS Chem. Neurosci. 2015, 6, 701-707.

[DOI]
181

"A Red-Shifted Photochromic Sulfonylurea for the Remote Control of Pancreatic Beta Cell Function" Broichhagen, J.; Frank, J. A.; Johnston, N. R.; Mitchell, K.; Smid, K.; Marchetti, P.; Bugliani, M.; Rutter, G. A.; Trauner. D.*; Hodson, D.* Chem. Commun. 201527, 6018- 6021.

[DOI]
180

"Calculated Nuclear Magnetic Resonance Spectra of Polytwistane and Related Hydrocarbon Nanorods" Maryasin, B.; Olbrich, M.; Trauner, D.*; Ochsenfeld, C.* J. Chem. Theory Comput. 201511, 1020-1026.

[DOI]
179

"Synthetic Studies Toward Polytwistane Hydrocarbon Nanorods" Olbrich, M.; Mayer, P.; Trauner, D. J. Org. Chem.201580, 2042-2055.

[DOI]

Highlighted as Front Cover

178

"Long Wavelength Optical Control of Glutamate Receptor Ion Channels Using a Tetra- Ortho-Substituted Azobenzene Derivative" Rullo, A.; Reiner, A.; Reiter, A.; Trauner, D.; Isacoff, E. Y.; Woolley, G. A. Chem. Commun. 201450, 14613-14615.

[DOI]
177

"Extraction of Photogenerated Electrons and Holes From a COF Integrated Heterojunction" Calik, M.; Auras, F.; Li, Y.; Salonen, L.; Bader, K.; Gill, I.; Handloser, M.; Medina, D.; Dogru, M.; Löbermann, L. M.; Trauner, Hartschuh, A.; D.; Bein, T. J. Am. Chem. Soc. 2014136, 51, 17802-17807.

[DOI]
176

"Synthetic Retinal Analogs Modify the Spectral and Kinetic Characteristics of Microbial Rhodopsin Optogenetic Tools" AzimiHashemi, N.; Erbguth, K.; Vogt, A.; Riemensperger, T; Rauch, E.; Woodmansee, D.; Nagpal, J.; Brauner, M.; Sheves, M.; Fiala, A.; Kattner, L.; Trauner, D.; Hegemann, P.; Gottschalk, A.; Liewald, J. F. Nature Commun. 20145, 5810.

[DOI]
175

"Photochemical Formation of Intricarene" Stichnoth, D.; Kölle, P.; Kimbrough, T. J.; Riedle, E.; de Vivie-Riedle, R.; Trauner, D. Nature Commun. 20145, 5597.

[DOI]
174

"Biomimetic Synthesis of the Calcineurin Phosphatase Inhibitor Dibefurin" Ellerbrock, P.; Armanino, N.; Trauner, D. Angew. Chem. Int. Ed. 201453, 13414-13418.

[DOI]
173

"Optical Control of Insulin Release Using a Photoswitchable Sulfonylurea" Broichhagen, J.; Schönberger, M.; Frank, J.; Marchetti, P.; Bugliani, M.; Shapiro, A. M. J.; Trapp, S.; Rutter, G.; Hodson, D. J.*; Trauner, D.* Nature Commun. 20145, 5116, DOI: 10.1038/ncomms6116.

[DOI]
172

"A Zinc Phthalocyanine-Based Periodic Mesoporous Organosilica Exhibiting Charge Transfer to Fullerenes" Auras, F.; Li, Y.; Löbermann, F.; Döblinger, M.; Schuster, J.; Peter, L. M.; Trauner, D.*; Bein, T.* Chem. Eur. J. 201420, 14971-14975.

[DOI]
171

"The in vivo Chemistry of Photoswitched Tethered Ligands" Broichhagen, J.; Trauner, D.Curr. Opin. Chem. Biol. 201421, 121-127.

[DOI]
170

"Total Synthesis of the Proposed Structure of Trichodermatide A" Myers. E.; Herrero- Gómez, E.; Baitinger, I.; Lachs, J.; Mayer, P.; Hanni, M.; Ochsenfeld, C.; Trauner, D.J. Org. Chem. 201479, 9812-9817.

[DOI]

Highlighted in Synfacts

169

"A Pentasymmetric Open Channel Blocker for Cys-Loop Receptor Channels" Carta, V.; Pangerl, M.; Baur, R.; Puthenkalam, R.; Ernst, M.; Trauner, D.*; Sigel E.* PLoS ONE 2014, DOI: 10.1371/journal.pone.0106688.

[DOI]
168

"Relative Positioning of Classical Benzodiazepines to the γ2‐Subunit of GABA-A Receptors" Middendorp, S. J.; Hurni, E.; Stein, M.; Pangerl, M.; Trauner, D.; Sigel E. ACS Chem. Biol. 2014, 9, 1846-1853.

[DOI]
167

"Controlling Epithelial Sodium Channels With Light Using a Photoswitchable Amiloride" Schönberger, M.; Althaus, M., Fronius, M.; Clauss, W., Trauner, D. Nature Chemistry 20146, 712-719.

[DOI]
166

"The Total Synthesis of (–)-Nitidasin" Hog, D.; Huber. F.; Mayer, P.; Trauner, D. Angew. Chem. Int. Ed. 201453, 8413-8517.

[DOI]

Highlighted in Synfacts

165

"Der Schattensammler. Die allerletzte Autobiografie. By Carl Djerassi (Book Review)"Angew. Chem. Int. Ed. Engl. 201453, 2808.

[DOI]
164

"Development of a New Photochromic Ion Channel Blocker via Azologization of Fomocaine" Schönberger, M.; Damijonaitis, A.; Zhang, Z.; Nagel, D.; Trauner, D. ACS Chem. Neurosci. 20145, 515-518.

[DOI]
163

"Development of an Iron(II)-Catalyzed Aerobic Catechol Cleavage and Biomimetic Synthesis of Betanidin" Guimond, G.; Mayer, P.; Trauner, D. Chem. Eur. J. 2014, 20, 9519-9523.

[DOI]
162

"Optical Control of Acetylcholine Esterase with a Tacrine Photoswitch" Broichhagen, J.; Jurastow, I.; Iwan, K.; Kummer, W.; Trauner, D. Angew. Chem. Int. Ed. 201453, 7657- 7660.

[DOI]
161

"Biomimetic Synthesis of (±)-Merochlorin B" Meier, R.; Strych, S.; Trauner, D. Org. Lett.201416, 2634-2637.

[DOI]
160

"Ligand Photo-Isomerization Triggers Conformational Changes in iGluR2 Ligand Binding Domain" Wolter, T.; Steinbrecher, T.; Trauner, D.; Elstner, M. PLOS One 20149, e97216.

[DOI]
159

"Finding Function and Form (Editorial)” Trauner, D. Nat. Prod. Rep. 2014, 31, 411-413.

[DOI]
158

"A Robust Route towards Functionalized Pyrrolizidines as Precursors for Daphniphyllum Alkaloids" Pangerl, M.; Höhlein, I.; Trauner, D. Synlett 2014eFirst.

[DOI]
157

"Restoring Visual Function in Blind Mice With a Photoswitch That Exploits Electrophysiological Remodeling of Retinal Ganglion Cells" Tochitsky, I.; Polosukhina, A.; Degtyar, V. E.; Gallerani, N.; Smith, C. M.; Friedman, A.; Van Gelder, R. N.; Trauner, D.; Kaufer, D.; Kramer R. H. Neuron 201481, 800-813.

[DOI]
156

"A Photochromic Agonist of μ-Opioid Receptors" Schönberger, M.; Trauner, D. Angew. Chem. Int. Ed. 2014, 53, 3264-3267.

[DOI]
155

"Polytwistane" Barua, S. R.; Quanz, H.; Olbrich, M.; Schreiner, P. R.; Trauner, D.; Allen, W.D. Chem. Eur. J. 201420, 1638-1645.

[DOI]
154

"A Step Toward Polytwistane: Synthesis and Characterization of C2-Symmetric Tritwistane" Olbrich, M.; Mayer, P.; Trauner, D. Org. Biomol. Chem. 2014, 12, 108-112.

[DOI]

Highlighted in Synfacts

153

"Toward the Total Synthesis of Ansalactam A" Hager, A.; Kuttruff, C. A.; Herrero-Gomez, E.; Trauner, D. Tetrahedron Lett. 2014, 55, 59-62.

[DOI]
152

"Total Synthesis of Sandresolide B and Amphilectolide" Chen, I. T.; Baitinger, I.; Schreyer, L.; Trauner, D. Org. Lett. 2014, 16, 166-169.

[DOI]
151

"A Photoswitchable Neurotransmitter Analogue Bound to its Receptor" Reiter, A.; Skerra, A., Trauner, D.*; Schiefner, A.* Biochemistry 201352, 8972-8974.

[DOI]
150

"Bilirubin in a New Light" Broichhagen, J.; Trauner, D. Angew. Chem. Int. Ed. 2013, 53, 13868-13070.

[DOI]
149

"Challenges and Opportunities in Optochemical Genetics" Isacoff, E.; Kramer, R.; Trauner, D. in Optogenetics, Hegemann, P., Sigrist, S. eds., De Gruyter 2013, pp. 35-46.

[DOI]
148

"A Red-Shifted, Fast-Relaxing Azobenzene Photoswitch for Visible Light Control of an Ionotropic Glutamate Receptor" Kienzler, M. A.; Reiner, A.; Trautman, E.; Yoo, S.; Trauner, D.*; Isacoff, E. Y.* J. Am. Chem. Soc. 2013135, 17683–17686.

[DOI]
147

"A Photoactive Porphyrin-Based Periodic Mesoporous Organosilica Thin Film" Li, Y.; Auras, F.; Löbermann, F.; Döblinger, M.; Schuster, J.; Peter, L. M.; Trauner, D.*; Bein, T.*J. Am. Chem. Soc. 2013135, 18513–18519.

[DOI]
146

"Total Synthesis of Herbicidin C and Aureonuclemycin: Impasses and New Avenues" Hager, D.; Paulitz, C.; Tiebes, J.; Mayer, P.; Trauner, D. J. Org. Chem. 2013, 78, 10784- 10801.

[DOI]
145

"Tetraphenylporphyrin Derivative Specifically Blocks Members of the Voltage-Gated Potassium Channel Subfamily Kv1" Hornig, S.; Ohmert, I.; Trauner, D.; Ader, C.; Baldus, M.; Pongs, O. Channels 2013, 7, 1-10.

[DOI]
144

"Toward the Total Synthesis of Divergolides C and D" Hager, A.; Kuttruff, C. A.; Hager, D.; Terwilliger, D. W.; Trauner, D. Synlett 2013, 24, 1915-1920.

[DOI]
143

"Intramolecular Vinyl Quinone Diels–Alder Reactions: Asymmetric Entry to the Cordiachrome Core and Synthesis of (−)-Isoglaziovianol" Löbermann, F.; Weisheit, L.; Trauner, D. Org. Lett. 201315, 4324-4326.

[DOI]
142

"Biomimetic Synthesis of Santalin A, B and Santarubin A, B, the Major Colorants of Red Sandalwood" Strych, S.; Trauner, D. Angew. Chem. Int. Ed. 201352, 9509-9512.

[DOI]

Synform: [DOI]

141

"Optical Control of TRPV1 Channels" Stein, M.; Breit, A.; Fehrentz, T.; Gudermann, T.; Trauner, D. Angew. Chem. Int. Ed. 2013, 52, 9845-9848

[DOI]
140

"Studies toward the Biomimetic Total Synthesis of (–)-PF-1018" Webster, R.; Gaspar, B.; Mayer, P.; Trauner, D. Org. Lett. 2013, 15, 1866-1869.

[DOI]
139

"Optical Control of Metabotropic Glutamate Receptors" Levitz, J.; Pantoja, C.; Gaub, B; Janovjak, H.; Reiner, A.; Hoagland, A.; Schoppik, D.; Kane, B.; Stawski, P.; Schier, A. F.; Trauner, D.*; Isacoff, E. Y.* Nat. Neurosci. 2013, 16, 507-516.

[DOI]
138

Optical Control of Calcium-Regulated Exocytosis" Izquierdo, M., Trauner, D., Llobet, A., Gorostiza, P. Biochim. Biophys. Acta 2013, 1830, 2853–2860.

[DOI]
137

"Characterization of a Diffusible Signaling Factor from Xylella Fastidiosa" Beaulieu, E. D.; Ionescu, M.; Chaterjee, S.; Yokota, K.; Trauner, D.; Lindow, S. mBio 20134, e00539-12.

[DOI]
136

"Optical Modulation of Neurotransmission Using Calcium Photocurrents Through the Ion Channel LiGluR" Izquierdo-Serra, M.; Trauner, D.; Lobet, A.; Gorostiza, P. Frontiers. Mol. Neurosci. 20136, doi: 10.3389/fnmol.2013.00003.

[DOI]
135

"A 1H-NMR Assay for Measuring the Photostationary states of Photoswitchable Ligands" Banghart, M., Trauner, D. Methods Mol. Biol. 2013995, 105-120.

[DOI]
134

"Mode of Cell Death Induction by Pharmacological Vacuolar H+-ATPase (V-ATPase) Inhibition" Von Schwarzenberg, K.; Wiedmann, R. M.; Zahler, S.; Trauner, D.; Vollmar, A. M. J. Biol. Chem. 2013, 288, 1385-1396.

[DOI]
133

"The V-ATPase-inhibitor Archazolid Abrogates Tumor Metastasis via Inhibition of Endocytic Activation of the Rho-GTPase Rac1" Wiedmann, R. M.; von Schwarzenberg, K.; Palamidessi, A.; Schreiner, L.; Kubisch, R.; Liebl, J.; Schempp, C.; Trauner, D.; Vereb, G.; Zahler, S.; Wagner, E. ; Muller, R. ; Scita, G.; Vollmar, A. M. Cancer Res. 2012, 72, 5976- 5987.

[DOI]
132

"Label-Free Microscale Thermophoresis Discriminates Sites and Affinity of Protein–Ligand Binding" Seidel, S. A.; Wienken, C. J.; Geissler, S.; Jerabek-Willemsen, M.; Duhr, S.; Reiter, A.; Trauner, D.; Braun, D.; Baaske, P. Angew. Chem. Int. Ed. 2012, 51, 10656- 10659.

[DOI]

CeNS Publication Award 2012. [PDF]

131

"The Crystal Structure of the Dess-Marin Periodinane" Schröckeneder, A., Stichnoth, D., Mayer, P.; Trauner, D. Beilstein J. Org. Chem., 20128, 1523-1527.

[DOI]
130

"Molecular Switches and Cages” Trauner, D. Beilstein J. Org. Chem, 20128, 870-871.

[DOI]
129

"Azo-Propofols: Photochromic Potentiators of GABAA Receptors" Stein, M.; Middendorp, S. J.; Carta, V.; Pejo, E.; Raines, D. E.; Forman, S. A.; Sigel, E.; Trauner, D. Angew. Chem. Int. Ed. 2012, 42, 10500-10504.

[DOI]

[Video]

128

"Evolution of a Synthetic Strategy for the Variecolortides" Kuttruff, C.; Mayer, P.; Trauner, D. Eur. J. Org. Chem. 201227, 5151-5161.

[DOI]
127

"Photochemical Restoration of Visual Responses in Blind Mice" Polosukhina, A.; Litt, J.; Tochitsky, I.; Nemargut, J.; Sychev, Y.; De Kouchkovsky, I.; Huang, T.; Borges, K.; Trauner, D.; Van Gelder, R. N.; Kramer R. H. Neuron 2012, 75, 271-282.

[DOI]

Highlighted in Nature 488, 8 (2012). Highlighted in C&EN 31, 12 (2012).

126

Exploring the Pharmacology and Action Spectra of Photochromic Open Channel Blockers" Fehrentz, T.; C.; Huber, F.M.E.; Kienzler, M.; Mayer, P.; Trauner, D. ChemBioChem201213, 1746-1749.

[DOI]
125

"A Unified Approach to trans-Hydrindane Sesterterpenoids" Hog, D. T., Mayer, P., Trauner, D. J. Org. Chem. 2012, 77, 5838-5843.

[DOI]
124

"Synthetic Approaches Toward Sesterterpenoids" Hog, D. T.; Webster, R.; Trauner, D. Nat. Prod. Rep. 2012, 29, 752-779.

[DOI]
123

"Stereoselective Total Syntheses of Herbicidin C and Aureonuclemycin Through Late Stage Glycosylation" Hager, D.; Mayer. P.; Trauner, D. Angew. Chem. Int. Ed. 201251,5625-6528.

[DOI]
122

“A Total Synthesis Prompts the Structure Revision of Haouamine B” Matveenko, M., Liang, G. Lauterwasser, E., Trauner, D. J. Am. Chem. Soc. 2012134, 9291–9295.

[DOI]
121

"A Photochromic Agonist of AMPA Receptors" Stawski, P.; Sumser, M.; Trauner, D.Angew. Chem. Int. Ed. 201251, 5748-5751.

[DOI]
120

"Rapid Optical Control of Nociception With an Ion Channel Photoswitch" Mourot, A.; Fehrentz, T., Bautista, D., Trauner, D.*, Kramer, R.*, Nature Methods, 20129, 396-402.

[DOI]
119

"An Approach to Aminonaphthoquinone Ansamycins Using a Modified Danishefsky Diene" Kuttruff, C. A., Geiger, S., Cakmak, M., Mayer, P., Trauner, D., Org. Lett. 201214, 1070- 1073.

[DOI]
118

"Total Synthesis of Exiguamines A and B Inspired by Catecholamine Chemistry" Sofiyev, V., Lumb, J.-P., Volgraf, M., Trauner, D., Chem. Eur. J., 2012, 18, 4999-5005.

[DOI]
117

"Optical Control of Genetically Engineered Nicotinic Acetyl Choline Receptors" Tochitsky, I.; Banghart M.R.; Mourot, A.; Zhao, J.Z.; Gaub, B.; Kramer, R.; Trauner, D., Nature Chemistry, 2012, 4, 105-111.

[DOI]
116

Optochemical Genetics" Fehrentz, T.; Schönberger, M.; Trauner, D., Angew. Chem. Int. Ed. 2011, 50, 12156-12182.

[DOI]
115

"LiGluR Restores Visual Responses in Rodent Models of Inherited Blindness" Caporale, N.; Kolstad, K. D.; Lee, T.; Tochitsky, I.; Dalkara, D.; Trauner, D.; Kramer, R.; Dan, Y.; Isacoff E. Y.; Flannery, J. G. Molecular Therapy 2011, 19, 1212–1219.

[DOI]
114

"Electrocyclic Reactions" Gaspar B., Trauner, D. in Science of Synthesis, Stereoselective Synthesis 3: Stereoselective Pericyclic Reactions, Cross Coupling, CH and CX Activation2011, Thieme: Stuttgart & New York, pp. 383-402.

[DOI]
113

"Switchable Proteins and Channels" Volgraf, M., Banghart, M., Trauner, D. in Molecular Switches, Second Edition. 2011, Vol. 2, Feringa, B. ed., Wiley-VCH: Weinheim, pp. 563- 593.

[DOI]
112

"Tuning Photochromic Ion Channel Blockers" Mourot, A.; Kienzler, M. A.; Banghart, M. R.; Fehrentz, T.; Huber, F. M. E.; Stein, M.; Kramer, R. H.; Trauner, D. ACS Chemical Neuroscience 2011, 2, 536-543.

[DOI]
111

"An Efficient Synthesis of Loline Alkaloids" Cakmak, M.; Mayer, P.; Trauner, D Nat. Chem.2011, 3, 543-545.

[DOI]
110

"Optogenetic Photochemical Control of Designer K+ Channels in Mammalian Neurons" Fortin, D. L.; Dunn, T. W.; Fedorchak, A; Allen, D.; Montpetit, R.; Banghart, M. R.; Trauner, D.; Adelman, J. P.; Kramer, R. H. J. Neurophys. 2011, 106, 488-496.

[DOI]
109

"Synthetic Studies Toward A-74528" Hager, A.; Mazunin, D.; Mayer, P.; Trauner, D. Org Lett2011, 13, 1386–1389.

[DOI]
108

"Crocipodin, a Benzotropolone Pigment From the Mushroom Leccinum Crocipodium (Boletales) " Kerschensteiner, L.; Löbermann, F.; Steglich, W.; Trauner, D. Tetrahedron 2011, 67, 1536-1539.

[DOI]
107

"Concise Total Synthesis of Variecolortide A and B Through an Unusual Hetero Diels- Alder Reaction" Kuttruff, C. A.; Zipse, H.; Trauner, D. Angew. Chem. Int. Ed. 2011 50, 1402-1405.

[DOI]
106

"Toward the Total Synthesis of Maoecrystal V: Establishment of Contiguous Quaternary Stereocenters" Baitinger, I. ; Mayer, P.; Trauner, D. Org. Lett. 2010, 12, 5656-5659.

[DOI]
105

"Theoretical Investigation of the Rubicordifolin Cascade" Lumb, J.-P.; Krinsky, J.; Trauner, D. Org. Lett. 2010, 22, 5162-5165.

[DOI]
104

"Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-gated Ion Channel" Hilf, R. J. C.; Bertozzi, C.; Zimmermann, I.; Reiter, A.; Trauner, D.; Dutzler, R.Nature Struct. Mol. Biol, 2010, 17, 1330-1337.

[DOI]
103

"Pharmacology of Ionotropic Glutamate Receptors: A Structural Perspective" Stawski P., Janovjak H., Trauner D. Bioorg Med Chem. 201018, 7759-7772.

[DOI]
102

"A Light-gated, Potassium-selective Glutamate Receptor for the Optical Inhibition of Neuronal Firing" Janovjak, H.; Szobota, S.; Wyart, C.; Trauner, D.; Isacoff, E. Y. Nature Neurosci. 201013, 1027–1032.

[DOI]
101

"A Signal Processing Analysis of Purkinje Cells In Vitro" Abrams, Z. R.; Warrier, A.; Trauner, D.; Zhang, X. Frontiers in Neural Circuits 20104, 1–13.

[DOI]
100

"Biomimetic Synthesis of (–)-Pycnanthuquinone C via Vinyl Quinone Diels-Alder Reaction" Löbermann, F.; Mayer, P.; Trauner, D. Angew. Chem. Int. Ed. 201049, 6199–6202.

[DOI]
99

"Total Synthesis of Newbouldine via Reductive N-N Bond Formation" Pangerl, M.; Chambers C. H.; Trauner, D. Tetrahedron 201066, 6626-6631.

[DOI]
98

"On the Development of Catalytic Carba-6π Electrocyclizations" Bishop, L. M.; Roberson, R. E.; Bergman, R. G.; Trauner, D. Synthesis 201013, 2233–2244.

[DOI]
97

"Total Synthesis of Coralloidolides A, B, C, and E" Kimbrough, T.J.; Roethle P.A.; Mayer, P.; Trauner, D., Angew. Chem. Int. Ed201049, 2619-2621.

[DOI]
96

"Photochromic Blockers of Voltage-Gated Potassium Channels" Banghart, M. R., Mourot, A.; Fortin, D. L.; Dunn, Kramer, R. H.; Trauner, D., Angew. Chem. Int. Ed200948, 9097– 9101.

[DOI]
95

"New Photochemical Tools for Controlling Neuronal Activity" Kramer, R.H.; Fortin, D.L.; Trauner, D. Curr. Opin. Neurobiol. 2009, 19, 1-9.

[DOI]
94

"Optogenetic Identification of Behavioral Module in the Vertebrate Spinal Cord" Wyart, C.; Del Bene, F.; Warp, E.; Scott, E. K.; Trauner, D., Baier, H.; Isacoff, E.Y., Nature2009,461, 407-410.

[DOI]
93

"Calix[4]arene-Based Conical-Shaped Ligands for Voltage Dependent Potassium Channels" Martos, V.; Bell, S. C.; Santos, E.; Isacoff, E.Y.; Trauner, D.*; de Mendoza, J.,Proc. Natl. Acad. Sci. USA 2009106, 10482-10486.

[DOI]
92

"Nanosculpting Reversed Wavelength Sensitivity Into a Photoswitchable iGluR" Numano, R.; Szobota, S.; Gorostiza, P.; Volgraf, M.; Trauner, D.*; Isacoff, E.Y., Proc. Natl. Acad. Sci. USA 2009106, 6814-6819.

[DOI]
91

"Total Synthesis of (±)-Rhazinal Using Palladium-Catalyzed Cyclizations" Bowie, A.L.; Hughes C.H.; Trauner, D., J. Org. Chem.200974, 1581-1586.

[DOI]
90

"Catalysis of 6p Electrocyclizations" Bishop, L. M.; Barbarow, J. E.; Bergman, R. G.; Trauner, D., Angew. Chem. Int. Ed200847, 8100-8103.

[DOI]
89

"Biomimetic Synthesis of the IDO Inhibitors Exiguamine A and B" Volgraf, M.; Lumb, J.-P., Brastianos, H.C.; Carr, G.; Chung, M.K.W.; Münzel, M.; Mauk, A.G.; Andersen, R.J.; Trauner, D., Nature Chem. Biol. 20084, 535-537.

[DOI]
88

"Ortho-Quinone Methides from para-Quinones: Total Synthesis of Rubioncolin B" Lumb, J.-P., Choong, K. P.; Trauner, D. J. Am. Chem. Soc2008130, 9230-9231

[DOI]
87

"Vinyl Quinones as Diels-Alder Dienes: Total Synthesis of (–)-Halenaquinone” Kienzler, M.A., Sueseno, S.; Trauner, D. J. Am. Chem. Soc2008130, 8604-8605.

[DOI]
86

"Introduction: Chemical Approaches to Neurobiology" Trauner, D., Chem. Rev. 2008105, 1499-1500.

[DOI]
85

"Mechanistic Investigations Into the Acid-Catalyzed Cyclization of a Vinyl Ortho-Quinone Methide" Bishop, L.M.; Houk, K.N.; Winkler, M.; Bergman, R.G.; Trauner, D. Chem. Eur. J.200814, 5405-5408.

[DOI]
84

"A Structural Link Between Inactivation and Block of a K+ Channel" Ader, C.; Schneider, R.; Hornig, S.; Velisetty, P.; Wilson; E. M.; Lange, A.; Giller, K.; Ohmert, I.; Martin- Eauclaire, M.-F.; Trauner, D.; Becker, S.; Pongs, O.; Baldus, M. Nature Struct. Mol. Biol.,200815, 605-612.

[DOI]
83

"The Chemistry of Marine Furanocembranoids, Pseudopteranes, Gersolanes, and Related Natural Products." Roethle, P. A.; Trauner, D. Nat. Prod. Rep200825, 298-317.

[DOI]
82

"Photochemical Control of Endogenous Ion Channels and Cellular Excitability" Fortin, D.L.; Banghart, M.R., Dunn, T.D.; Borges, K.; Wagnaar, D.A.; Gaudry, Q.; Karakossian, M.; Otis, T. W.; Kristan, W. B.; Trauner, D.*; Kramer, R. H.* Nature Meth. 20085, 331-338.

[DOI]
81

"Conjugate Addition of Allyl Stannanes with Concomitant Triflation" Beaulieu, E. D.; Voss, L.; Trauner, D. Org. Lett. 200810, 869-872.

[DOI]
80

"Biomimetic Synthesis of the Shimalactones" Sofiyev, V.; Navarro, G. Trauner, D. Org. Lett. 2008, 10, 149-152.

[DOI]
79

"Regulating Enzymatic Activity With a Photoswitchable Affinity Label " Harvey, J. Trauner, D. ChemBioChem20089, 191-193.

[DOI]
78

"Enolates" Trauner, D. in Science of Synthesis, Houben-Weyl, Methods of Molecular Transformations, Thieme: Stuttgart & New York, 2008Vol. 32, pp. 547-588.

[DOI]
77

"Enols" Trauner, D. in Science of Synthesis, Houben-Weyl, Methods of Molecular Transformations, Thieme: Stuttgart & New York2008Vol. 32, pp. 533-545.

[DOI]
76

"All Optical Interface for Parallel, Remote, and Spatiotemporal Control of Neuronal Activity" Wang, S.; Szobota, S.; Wang, Y.; Volgraf, M.; Liu, Z.; Sun, C.; Trauner, D.; Isacoff, E. Y.; Zhang, X. Nano Lett. 20077, 3859-3863.

[DOI]
75

"Photomechanical Switching of Individual Engineered Molecules at a Metallic Surface" Comstock, M.J.; Levy, N.; Kirakosian, A.; Cho, J.; Lauterwasser, F.; Harvey, J.H.; Strubbe, D.A.; Fréchet, J.M.J.; Trauner, D.; Louie, S.G.; Crommie, M.F. Phys. Chem Rev. Lett.,200799, 038301.

[DOI]
74

"Total Synthesis of (–)-Archazolid B" Roethle, P.A.; Chen, I.T.; Trauner, D. J. Am. Chem. Soc. 2007129, 8960-8961.

[DOI]
73

"Remote Control of Neuronal Activity With a Light-Gated Glutamate Receptor" Szobota, S.; Gorostiza, P.; Volgraf, M.; Fortin, D.; Tulyathan, O.; Kolstad, K.; Numano, R.; Aaron, H.; Ruzin, S.; Flannery J.; Kramer, R.H.; Baier, H.; Trauner, D.; Isacoff, E.Y. Neuron 2007,54, 535-545.

[DOI]
72

"Total Synthesis of Smenochromene B Through Ring Contraction" Rosa, C.P.; Kienzler, M.; Olson, B.S.; Liang, G.; Trauner, D. Tetrahedron 200763, 6529-6534.

[DOI]
71

"Mechanisms of Photoswitch Conjugation and Light Activation of an Ionotropic Glutamate Receptor" Gorostiza, P.; Volgraf, M.; Numano, R.; Szobota, S.; Trauner, D.*; Isacoff, E.Y.Proc. Natl. Acad. Sci. USA 2007104, 10865-10870.

[DOI]
70

"Synthesis of Functionalized Azobenzenes Through Cross-Coupling With Organotrifluoroborates" Harvey, J.H.; Butler, B.K.; Trauner, D. Tetrahedron Lett. 200748, 1661-1664.

[DOI]
69

"Concise Synthesis of the Bacterial DNA Primase Inhibitor (+)-Sch 642305" Wilson, E. M.; Trauner D. Org. Lett20079, 1327-1329.

[DOI]
68

"Reversibly Caged Glutamate: A Photochromic Agonist of Ionotropic Glutamate Receptors" Volgraf, M.; Gorostiza, P.; Szobota, S.; Helix, M.R.; Isacoff, E.Y.; Trauner, D. J. Am. Chem. Soc2007129, 260-261.

[DOI]
67

"The Meerwein-Eschenmoser-Claisen Rearrangement" Gradl, S.N.; Trauner D. in Claisen Rearrangements, Hiersemann, M.; Nubbemeyer, U. eds., Chapter 7; Weinheim: Wiley- VCH 2007.

[DOI]
66

"Total Synthesis of (–)-Heptemerone B and (–)-Guanacastepene E " Miller, A.K.; Hughes, C.H.; Kennedy-Smith, J.J.; Gradl, S.N.; Trauner, D. J. Am. Chem. Soc2006128, 17057- 17062.

[DOI]
65

"Engineering Light-Gated Ion Channels" Banghart, M.R.; Volgraf, M.; Trauner, D.Biochemistry 200645, 15129-15141.

[DOI]
64

"Exploring Biosynthetic Relationships Among Furanocembranoids: Synthesis of (–)- Bipinnatin J, (+)-Intricarene, (+)-Rubifolide, and (+)-Isoepilophodione B" Roethle, P. A.; Hernandez, P. T.; Trauner, D. Org. Lett20068, 5901-5904.

[DOI]
63

"Development of a Friedel-Crafts Triflation" Grundl, M.A.; Kaster, A.; Downs-Beaulieu, E.; Trauner, D. Org. Lett. 20068, 5429-5432.

[DOI]
62

"Photochemical Origin of SNF4435C/D and Formation of Orinocin through ‘Polyene Splicing" Müller, M; Kusebauch, B.; Liang, G.; Beaudry, C.M.; Trauner, D.; Hertweck. C. Angew. Chem. Int. Ed. 200645, 7835-7838.

[DOI]
61

"Mapping the Chemistry of Highly Unsaturated Pyrone Polyketides" Miller, A.K.; Trauner, D., Synlett 200614, 2295-2316.

[DOI]
60

"Light-Induced Depolarization of Neurons Using a Modified Shaker K Channel and a Molecular Photoswitch" Chambers, J. J.; Banghart, M. R.; Trauner, D.; Kramer, R. H. J. Neurophysiol. 200696, 2792-2796.

[DOI]
59

"Synthesis of Taiwaniaquinoids Via Nazarov Triflation" Liang, G.; Xu, Y.; Seiple, I.; Trauner, D. J. Am. Chem. Soc2006128, 11022-11023.

[DOI]
58

"Expedient Synthesis of (±)-Bipinnatin J" Roethle, P.A.; Trauner, D. Org. Lett20068,345-347.

[DOI]
57

"Synthetic Studies Toward the Haouamines" Grundl, M.A.: Trauner, D. Org. Lett20068,23-25.

[DOI]
56

"Allosteric Control of an Ionotropic Glutamate Receptor with an Optical Switch" Volgraf, M.; Gorostiza, P.; Numano, R.; Kramer R. H.; Isacoff. E.; Trauner, D. Nature Chem. Biol.20062, 47-52.

[DOI]

Featured in Science[DOI]

55

"Pericyclic Reactions of Prenylated Naphthoquinones: Biomimetic Syntheses of Mollugin and Microphyllaquinone" Lumb. J.P.; Trauner, D. Org. Lett20057, 5865-5868.

[DOI]
54

"Photochemical Tools for Remote-Control of Ion Channels in Excitable Cells" Chambers, J.J.; Trauner, D. , Kramer, R.H. Nature Chem. Biol20051, 360-365.

[DOI]
53

"Biosynthetic and Biomimetic Electrocyclizations" Beaudry, C.M.; Malerich, J.P.; Trauner, D. Chem. Rev. 2005105, 4757-4778.

[DOI]
52

"Concise Synthesis of (±)-Rhazinilam Through Direct Coupling" Bowie, A.L.; Hughes C.H.; Trauner, D. Org. Lett. 2005, 7, 5207-5209.

[DOI]
51

"Photosensitized Conversion of 9,10-Deoxytridachione to Photodeoxytridachione" Zuidema, D.R.; Miller, A.K.; Trauner D.; Jones P.B. Org. Lett. 20057, 4959-4962.

[DOI]
50

"Total Synthesis of (–)-SNF4435 C and (+)-SNF4435 D" Beaudry, C.M.; Trauner, D. Org. Lett2005, 74475-4477.

[DOI]
49

"A Glimpse at the Grail" Trauner, D. Nature Chem. Biol. 20051, 189-191.

[DOI]
48

"Infrared Hole Burning and Conformational Change in a Borane-Ammonia Complex" Endicott, C.A.; Strauss, H.L.; Hughes, C.C; Trauner, D.; J. Phys. Chem. B 2005109, 7714-7717.

[DOI]
47

"An Electrochemical Approach to the Guanacastepenes" Hughes, C.C.; Trauner, D. Org. Lett. 20057, 3425-3428.

[DOI]
46

"Mining the T etraene Manifold: T otal Synthesis of Complex Pyrones from Placobranchus ocellatus" Miller, A.K.; Trauner, D. Angew. Chem. Int. Ed. 200544, 4602-4606.

[DOI]
45

"Biomimetic Synthesis of Elysiapyrones A and B" Barbarow, J. E.; Miller, A. K.; Trauner, D.Org. Lett. 20057, 2901-2903.

[DOI]
44

"Stereoselective Synthesis of the Bioactive Polypropionates Aureothin, N- Acetylaureothamine and Aureonitrile" Liang, G.; Seiple I. B.; Trauner, D. Org. Lett. 2005,7, 2837-2839.

[DOI]
43

"Rational Design of a Chiral Pd(0)-Olefin Complex of Unprecedented Stability" Grundl, M.; Kennedy-Smith, J.J.; Trauner, D. Organometallics200524, 2831-2833.

[DOI]
42

"Biomimetic Synthesis of Antimalarial Naphthoquinones" Malerich, J.P.; Maimone, T.J.; Elliott, G.I.; Trauner D. J. Am. Chem. Soc. 2005127, 6276-6283.

[DOI]

Correction: [DOI]

41

"Dienophile Twisting Causes Rate Enhancements in Intramolecular Diels-Alder Cycloadditions: A DFT Study" Khuong, K.S.; Beaudry, C.; Trauner, D.*; Houk, K.N. J. Am. Chem. Soc. 2005127, 3688-3689.

[DOI]
40

"Stereoselective Synthesis of the Cyercene A and Placidenes" Liang, G.; Miller, A.K.; Trauner, D. Org. Lett. 20057, 819-821.

[DOI]
39

"Biomimetic Synthesis and Structure Elucidation of Rubicordifolin, a Cytotoxic Natural Product from Rubia cordifolia" Lumb, J.P.; Trauner, D. J. Am. Chem. Soc. 2005127, 2870-2871.

[DOI]
38

"Concise Synthesis of (±)-Smenochromene D (Likonide B)" Olson, B.S.; Trauner D.Synlett 2005700-702.

[DOI]
37

"Biomimetic Synthesis of Natural Products Isolated from Bignoniaceae" Malerich, J.; Trauner D. in Strategies and Tactics in Organic Synthesis2004Vol. 5, Harmata, M. ed., Elsevier: Amsterdam & New York, pp. 417-436.

[DOI]
36

"Light-Activated Ion Channels for Remote Control of Neuronal Firing" Banghart, M.R., Borges, K.; Isacoff. E., Trauner, D.*; Kramer, R.H.* Nature Neurosci. 20047, 1381-1386.

[DOI]

Featured in Science[DOI]

35

"Palladium-Catalyzed Couplings to Nucleophilic Heteroarenes: The Total Synthesis of (–)- Frondosin B" Hughes, C.C.; Trauner, D. Tetrahedron 200460, 9675-9686.

[DOI]
34

"Enantioselective Nazarov Cyclizations Reactions through Catalytic Asymmetric Proton Transfer" Liang, G.; Trauner D. J. Am. Chem. Soc. 2004126, 9544-9545.

[DOI]
33

"The Total Synthesis of (–)-Crispatene" Miller, A.K.; Byun, D.H.; Beaudry, C.M.; Trauner, D. Proc. Natl. Acad. Sci. USA 2004101, 12019-12023.

[DOI]
32

"Metabolic Modulation of Potassium Channels" Trauner, D.; Kramer, R.H. Science STKE, 2004 233, pe20.

[DOI]
31

"Efficient Nazarov Cyclizations of 2-Alkoxy-1,4-pentadien-ones" Liang, G.; Gradl, S.N.; Trauner, D. Org. Lett. 20035, 4931-4934.

[DOI]
30

"Potassium Channels: Symmetric, Selective and Sensitive" Trauner, D. Angew. Chem. Int. Ed. 200342, 5671-5675.

[DOI]
29

"Direct Catalytic Asymmetric Amination of Aldehydes: Synthesis of Evans Oxazolidinones and a-Amino Acids" Hughes, C.C.; Trauner D. Chemtracts 200316, 511-517.

[DOI]
28

"Synthetic Studies Toward the Guanacastepenes" Hughes, C.C.; Kennedy-Smith, J.J.; Trauner D. Org. Lett. 20035, 4113-4115.

[DOI]
27

"Protein Surface Recognition by Rational Design: Nanomolar Ligands for Potassium Channels" Gradl, S.N.; Felix, J.P., Isacoff, U.; Garcia, M.L.; Trauner, D. J. Am. Chem. Soc.2003125, 12668-12669.

[DOI]
26

"Reductive Cyclization of d-Hydroxy Nitriles: A New Synthesis of Glycosylamines" Dorsey, A.D.; Barbarow, J.E.; Trauner, D. Org. Lett. 20035, 3237-3239.

[DOI]
25

"Biomimetic Synthesis of Pinnatal and Sterekunthal A" Malerich, J.P.; Trauner D. J. Am. Chem. Soc., 2003125, 9554-9555.

[DOI]
24

"Intramolecular Diels-Alder Reactions of 5-Vinyl-1,3-cyclohexadienes" Ng. S.M.; Beaudry, C.M.; Trauner, D. OrgLett20035, 1701-1704.

[DOI]
23

"Development of Novel Lewis Acid Catalyzed Cycloisomerizations: Synthesis of Bicyclo[3.1.0] hexenes and Cyclopentenones" Miller, A.K.; Banghart, M.R.; Beaudry, C.M.; Suh, J.K.; Trauner, D. Tetrahedron 200359, 8919-8930.

[DOI]
22

"Total Synthesis of (±)-Photodeoxytridachione Through a Lewis Acid Catalyzed Cyclization" Miller, A. K.; Trauner, D. Angew. Chem. Int. Ed. 200342, 549-552.

[DOI]
21

"Enzymatic Desymmetrization of a Centrosymmetric Diacetate" Böhm, C.; Austin, W. F.; Trauner, D. Tetrahedron Asymmetry200314, 71-74.

[DOI]
20

"Borane-Ammonia Complexes Stabilized by Hydrogen Bonding" Hughes, C.C.; Scharn, D.; Mulzer, J.; Trauner D. Org. Lett. 20024, 4109-4111.

[DOI]
19

"The Total Synthesis of (–)-Amathaspiramide F" Hughes, C.C.; Trauner D. Angew. Chem. Int. Ed. 200241, 4556-4559.

[DOI]
18

"Synthetic Studies Toward SNF4435 C and SNF4435 D" Beaudry, C.M.; Trauner, D. Org. Lett. 20024, 2221-2224.

[DOI]
17

"Concise Total Synthesis of (–)-Frondosin B Using a Novel Palladium Catalyzed Cyclization" Hughes, C.C.; Trauner, D. Angew. Chem. Int. Ed. 200241, 1569-1572.

[DOI]
16

"A Practical Variant of the Claisen-Eschenmoser Rearrangement: Synthesis of Un- saturated Morpholine Amides" Gradl, S.N., Kennedy-Smith, J.J.; Kim, J.; Trauner, D. Synlett 2002, 411-414.

[DOI]
15

"Concise Stereoselective Routes to Advanced Intermediates Related to Natural and Unnatural Pinnaic Acid". Carson, M.W.; Hentemann, M.F.; Kim, G.; Trauner, D.; Danishefsky, S.J. Angew. Chem. Int. Ed. 200140, 4450-4552.

[DOI]
14

"The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study and Applications in Natural Product Synthesis". Chemler, S.R.; Trauner, D.; Danishefsky, S.J. Angew. Chem. Int. Ed. 200140, 4544-4568.

[DOI]
13

"On the Conformations of Halichlorine and the Pinnaic Acids: Nitrogen Inversion as a Possible Determinant of Biological Profile." Trauner, D.; Danishefsky, S.J. Helv. Chim. Acta 200083, 2344-2351.

[DOI]
12

"Synthesis of Immunomodulatory Marine Natural Products". Danishefsky, S. J.; Inoue, M.; Trauner, D. in "The Role of Natural Products in Drug Discovery", Ernst Schering Research Foundation (ESRF) Workshop 32, Springer: Heidelberg & New York, 2000, pp. 1-24.

[DOI]
11

"Morphine Synthesis and Biosynthesis - an Update". Novak, B.H.; Hudlicky, T.; Reed, J.W.; Mulzer, J.; Trauner, D. Curr. Org. Chem. 20004, 343-362.

[DOI]
10

"Total Synthesis of (+)-Halichlorine, an Inhibitor of VCAM-1 Expression" Trauner, D.; Schwarz, J.B.; Danishefsky, S.J. Angew. Chem. Int. Ed199938, 3542-3545.

[DOI]
9

"Studies Towards the Total Synthesis of Halichlorine: Asymmetric Synthesis of the Spiroquinolizidine Subunit" Trauner, D.; Danishefsky, S.J. Tetrahedron Lett. 199940, 6513-6516.

[DOI]
8

Insight into the Mechanism of the Saegusa Oxidation: Isolation of a Novel Palladium(0) Tetraolefin Complex" Porth, S.; Bats, J.W.; Trauner, D.; Giester, G.; Mulzer, J. Angew. Chem. Int. Ed. 199938, 2015-2016.

[DOI]
7

"Practical Synthesis of (–)-Morphine". Mulzer, J.; Trauner. D. Chirality 199911, 475-482.

[DOI]
6

"About the Use of Molecular Workbenches and Platforms in Organic Synthesis" Mulzer, J.; Schein, K.; Böhm, I.; Trauner, D. Pure Appl. Chem. 199870, 1487-1493.

[DOI]
5

"Synthesis of Enantiomerically Pure Morphine Alkaloids: The Hydrophenanthrene Route" Trauner, D.; Bats, J.W.; Werner, A.; Mulzer, J. J. Org. Chem.199863, 5908-5918.

[DOI]
4

"New Ventures in the Construction of Complex Heterocycles: Synthesis of Morphine- and Hasubanan Alkaloids" Trauner, D.; Porth, S.; Bats, J.W.; Giester, G.; Mulzer, J. Synthesis1998, 653-664.

[DOI]
3

"The Phenanthrenone Approach to Opium Alkaloids: Formal Total Synthesis of Morphine by Sigmatropic Rearrangement" Mulzer, J.; Bats, J.W.; List, B.; Opatz, T.; Trauner, D.Synlett 1997, 441-444.

[DOI]
2

"Formal Total Synthesis of (–)-Morphine by Cuprate Conjugate Addition" Mulzer, J.; Dürner, G.; Trauner, D. Angew. Chem. Int. Ed. 199635, 2830-2832.

[DOI]
1

"StereoselectiveInsertion of Ketenes into O,O-Acetals: Synthesis of b-Alkoxy Esters and 1,4-dioxepanones" Mulzer, J.; Trauner, D.; Bats, J.W. Angew. Chem.Int. Ed. 1996, 35, 1970-1972.

[DOI]